Nasal NK/T Cell Lymphoma Presenting with Perforation of Palate: A Case Report and Review of Literature
Published: March 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/24011.9356
Shreyas N Shah, Priyank R Mistry, Girish R Chauhan, Vishal Chauhan, Jayshankar Pillai
1. Assistant Professor, Department of Oral Pathology, Km Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
2. Senior Resident, Department of Ear, Nose and Throat, Parul Institute of Medical Sciences and Research, Vadodara, Gujarat, India.
3. Assistant Professor, Department of Oral Pathology, Government Dental College and Hospital, Jamnagar, Gujarat, India.
4. Assistant Professor, Department of Prosthodontics, Government Dental College and Hospital, Ahmedabad, Gujarat, India.
5. Tutor, Department of Oral Pathology, Government Dental College and Hospital, Ahmedabad, Gujarat, India.
Correspondence
Dr. Priyank R Mistry,
Senior Resident, Department of Ear, Nose and Throat, Parul Institute of Medical Sciences and Research, Vadodara-391760,
Gujarat, India.
E-mail: priyankmistry_09@yahoo.co.in
Nasal Natural Killer (NK)/T cell lymphoma, commonly mentioned in the literature as Lethal Midline Granuloma (LMG) is an unusual pathology of the oro-maxillo-facial region characterized by aggressive and progressive destruction of the face, nose, palate and pharynx. This disease is now classified as a T-cell lymphoma based on modern cytogenetics, immunologic and molecular studies. However, it is mentioned in various literatures by various names. Here, we present one such clinically diagnosed, histopathologically and immunologically confirmed case of LMG, designated as NK/T cell lymphoma in a 56-year-old male. The uncommon presentation of NK/T cell lymphomas should be kept as a differential diagnosis for management of patients.
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